Hardware Systems Integration Engineer

About the Lighthouse Partnership
The Lighthouse Partnership, launched in 2024 by the Wyss Center, is a strategic initiative dedicated to advancing AI-driven neuromodulation for neurological and mental health disorders. It brings together a multidisciplinary team of over 40 scientists, engineers, and researchers from the Campus Biotech Brain Health community, in collaboration with leading institutions in Western Switzerland, including EPFL, CHUV, UNIGE, HUG, and Fondation Campus Biotech Geneva. With a strong focus on circuit neuroscience, neuroengineering, and neuroAI, the partnership is committed to translating scientific and engineering breakthroughs into novel therapeutic solutions.

About the Position
We are seeking a highly skilled, hands-on Systems Integration Engineer to join the Lighthouse Partnership team. In this role, you will be responsible for the hardware integration and assembly of complex neuromodulation systems, ensuring seamless communication and functionality across hardware and software components. This includes designing and implementing the physical integration of the different hardware components, creating a cohesive and fully functional system. You will work closely with a multidisciplinary team of engineers, neuroscientists, and clinicians to develop and test innovative solutions that advance the treatment of neurological disorders. Specifically, you will contribute to two neuromodulation projects, to be validated in preclinical models: a Brain-Spine digital bridge to restore mobility in paralysis and an optogenetic therapy for peripheral nerve disorders, targeting spasticity.

The ideal candidate will have hands-on experience in system integration for medical devices, excellent problem-solving skills, and a strong background in electrical engineering and neurotechnology or related fields. A strong system-level perspective and the ability to align and coordinate the work of diverse research teams are essential for success in this role.

Key responsibilities
Design for Packaging: Collaborate with all stakeholders to coordinate design input, ensuring that individual components (e.g., chips, electronic boards) are produced in compliance with assembly and integration requirements.
System Integration: Lead and execute the integration of hardware and software components into a unified neuromodulation platform, ensuring cohesive system functionality. This includes developing connection schemes, assembling systems, integrating thin-film technologies with advanced silicon chips, selecting appropriate electronic components, defining communication protocols between different components of the system, and designing miniaturized Printed Circuit Boards (PCBs).
Testing and Validation: Conduct hands-on testing, troubleshoot integration issues, and refine hardware designs. Validate prototypes to ensure suitability for preclinical testing in animal models.
Collaboration: Work closely with cross-functional teams, including hardware engineers, data scientists, clinicians, and external partners to ensure effective system design and functionality. Align and coordinate efforts of various research teams to ensure a consistent system-level perspective.
Compliance: Thoroughly document integration processes to facilitate a seamless transition into the Wyss Center's Quality Management System, ensuring compliance with regulatory and quality standards.

Required Competence and Experience:
Degree: Bachelor's or master's degree in biomedical engineering, electrical engineering, microtechnology, or related field.
Experience: 3+ years in system integration, preferably in medical devices or neurotechnology (industry experience a plus).
Technical Skills: Hands-on expertise in hardware-software integration, system testing methodologies, PCB design, and debugging using electronics lab equipment (soldering, multimeters, oscilloscopes, logic/spectrum analyzers).
Collaboration & Problem-Solving: Proven ability to work in multidisciplinary teams, troubleshoot complex integration issues, and drive solutions.
Communication: Excellent written/verbal English skills (French is a plus).
Additional Competence (Nice to Have):
Experience with neuromodulation technologies.
Experience with implantable or wearable neurotechnology devices.

About the Wyss Center for Bio and Neuroengineering, Geneva, Switzerland
The Wyss Center is an independent, non-profit, research organization that innovates and accelerates technologies and therapies to transform the lives of people with neurological and mental health disorders. The Center pursues transformational technologies in artificial intelligence, bio- and neuroengineering to restore essential neural functions and deliver precision therapeutics for people with debilitating neurological and mental health disorders.

Based at Campus Biotech in Geneva, Switzerland, the Wyss Center partners with faculty, clinicians and industry, in Switzerland and internationally, to drive innovation and maximize clinical impact. The Wyss Center was established by a generous donation from the Swiss entrepreneur and philanthropist Hansjörg Wyss in 2014. Additional resources from funding agencies and other sources help the Wyss Center accelerate its mission.

To apply, please send your CV and cover letter to HR@wysscenter.ch no later than 13 March 2025.